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1. LAMBDA Laboratory Instruments

LAMBDA develops innovative, high quality laboratory instruments with an excellent price to performance ratio: laboratory fermentor, fermenters, bioreactor for cell culture, peristaltic pumps, syringe pumps, fraction collectors, powder dosing (powder pump), mass flow gas controllers and fermentation software for biotechnology, microbiology, food…

2. INNOVATION of the year 2007

Diploma for the LAMBDA MINIFOR laboratory bioreactor/fermenter on the competition “INNOVATION of the year 2007” held in Prague on 7th December 2007.

3. Prices

4. Demand form

You can use this demand form to request information about product you would like to purchase. Our consultant will contact you in 48 hours.

5. Software

Fermentation Software FNet is a software for monitoring fermentation and cell culture processes with the LAMBDA MINIFOR laboratory fermenter. Runs under Windows NT, 2000, XP, Vista, 7 and 8. All the information (actual values, set points, graphs, alarms) of the fermenter is presented in the main window : Actual values like temperature, pH, pO 2…

6. Artificial sun for cell cultures heating

The LAMBDA MINIFOR fermenter / bioreactor provides a new heating system for precise, fast and economic heating of the culture medium in fermentation and cell culture processes. From your own practical laboratory experience you may be familiar with the common problems when it comes to heating culture media in fermenters and bioreactors: The direct…

7. Industrielle Biotechnologie in Vienna

LAMBDA presented the innovation of the laboratory bioreactor MINIFOR at the conference 'Industrielle Biotechnologie - Eine Chance für Österreich?' in Vienna ( www.lisavr.at )

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9. Laboratory Bioreactor MINIFOR

The World‘s most innovative Bioreactor for your lab Based on over thirty years of personal experience in the field, we have tried to analyze what is necessary for efficient, modern bioreactors and select the best technical solutions, which would lead to best performance. We have invested a major effort to make our bioreactors more efficient and…

10. LAMBDA Credo

"Money making" is not the primary goal of LAMBDA! LAMBDA principles are not primarily based on profit maximization, but to support our customers with our skills, experience and knowledge

11. Easy Sterility Concept - Laboratory Fermentor-Bioreactor LAMBDA MINIFOR

An easy way to maintain the sterility of the cell culture for a long time ... How is it possible? By eliminating the critical points causing contamination in common fermenters and bioreactors. LAMBDA MINIFOR offers: Complete physical closure of the vessel and the side necks LAMBDA double-seal PEEK tubing connector Permanent stoppers with multiple…

12. Extremely compact fermentor-bioreactor system LAMBDA MINIFOR

Do you have space for a sheet of A4 paper on your laboratory bench? Then, there’s still enough place for the MINIFOR fermentor – bioreactor! Perfect parameter control and smallest footprint Minimum bioreactor foot print comparable to the size of an A4 sheet of paper (220 x 400 mm) Weighs only 7.5 kg - watch it closely, it could be carried away…

13. LAMBDA MINIFOR fermentor-bioreactor - Optimized vessel design

Unprecedented volume range from 35 ml to 6 liters Switch vessel volume at LOW COST Your Benefits Economical & Flexible solution at laboratory stage Elimination of complex and expensive head plates Optimized, user friendly vessel design Unique ergonomic easy sterility concept minimizing contamination Reduced heating, cooling and sterilization…

14. Antifoam Control System for the MINIFOR laboratory fermentor-bioreactor

Saves both money and valuable bench space around the MINIFOR laboratory fermentor-bioreactor with ' World smallest antifoam control system ' PRINCIPLE: Presence of foam is detected by the measurement of increase in electrical conductivity.   No need of an expensive anti-foam probe Simply two needles of the fermentor vessel are used as electrodes…

15. Sun-like way of heating

Infra-red heat rays provide soft heating and optimal temperature maintenance A big 'NO' to heating blankets, jacketed vessels and thermal circulating baths! Why? Very expensive and voluminous Overheating of the medium Prevents natural cooling and a complementary cooling is required Restricted view into the vessel More heat is dissipated outside…

16. MINI-4-GAS AUTOMATIC GAS-MIX

Build up your own high quality gas station! Free selection of gases Individual flow rates per gas Pressure independent flow rate measurement Stand-alone & programmable or remote control by industrial fermentation software SIAM Which gas do your cells need? CO 2 , O 2 , N 2 , Air pO 2 control & O 2 enrichment pH control by CO 2 Constant gas…

17. Process control software for monitoring fermentation and cell culture processes

Process control software for monitoring fermentation and cell culture processes  (pdf for download)

18. Fish-Tail Agitator

Unique bio-mimicking 'Fish-tail' bioagitator : - highly efficient mixing without eddies - free of cutting edges - produces no shear stress 'Fish-Tail' Agitator Did you know, it took over 500 millions years for nature to develop a perfect fish tail for energy transmission in the water? Only LAMBDA uses this know-how of nature to produce a unique…

19. Watch your cells grow!

Watch your cells grow! Pump flow INTEGRATOR – an economical alternative to Optical Density (OD) measurements During fermentation, cells produce acid or base which needs to be compensated. The INTEGRATOR in the pump integrates the amount of added acid or base. These data allow to assess cell growth or biotransformation with a precision similar…

20. A practical guide to select the bioreactor for stem cell culture

A practical guide to select the bioreactor for stem cell culture While purchasing a bioreactor (stem cell): For CHO, HeLa, HEK-293 and other cell lines consider gentle mixing , smallest volume possible , sterility, ideal gas mix, efficient gas exchange, exchangeable vessel volume at low cost, peristaltic pumps for long runs, precise temperature…

21. 1 Delivery check and Inspection

1 Delivery check and Inspection 1.1 Check the boxes and the equipment After receiving the order, inspect the boxes carefully and also the culture vessel and the other parts made of glass for any damages that may have occurred during shipping. In case of damages, please report to your local p urchasing department immediately or send us your claim…

22. Complete manual

Chapter 1 Chapter 2 Chapter 3

23. 2 Introduction

2.1 MINIFOR Design concept LAMBDA MINIFOR fermentor-bioreactor, designed for bench-top surfaces in laboratories is suitable for volumes from as low as 35 ml to 6.5 l. LAMBDA MINIFOR fermentor - bioreactor has been designed such that several of these can be placed side by side and are well suited for the optimization of bio-transformations and…

24. Syringe Pump

Infusion pump, filling pump with excellent price-performance ratio. This syringe pump using new VIT-FIT fixing system allows almost any syringe to be used from micro syringes to large volume syringes without the need of an adapter. The syringe is being held in both directions – infusion and filling – and it is handled very easily. There is a…

25. Fraction Collector

Experience new concept of fraction collector and collect fractions in any racks of your choice and unlimited number of fractions in single or multiple fractions. Omnicoll is the only fraction collector which can be programmed for any rack or recipients. All electronic and mechanical components have been miniaturised and placed in one moving part…

26. Powder Doser

The LAMBDA DOSER is a unique programmable pump for free-flowing solid substances. It allows the automatic or continuous addition of powders, powdery and crystalline substances without a spoon. Composed of a dosing unit coupled to a stepping motor controlled by modern electronics, allows constant and reproducible dosing even of solids which do not…

27. Lambda YELLOW SERVICE

Lambda Yellow Service  offers a full maintenance and support program designed to ensure maximum uptime, ease of operation, lowest total cost of ownership and continued productivity enhancements. Since it is not very reasonable to keep a service centre in every country (especially when such a service centre has almost nothing to do) we have…

28. Stop GOOGLing – Start LAMBDing!

You have found the requested laboratory instrument on our pages. Now you can discuss further details or inquiries directly with us: Just ask your questions simply and spontaneously in our live chat tool , we’ll be there to assist you personally.

29. Mass Flow Controller

A new mass flow controller system especially designed for use with Lamda bioreactors and fermentors. It allows control of the pH of a cell culture by controlled addition of gaseous CO2, the control of dissolved oxygen by regulation of the airflow or any other gas with a suitable controller. It can also be used independently, since all its…

30. Laboratory fermentation and cell culture kits and accessories

Fermentation and cell culture kits of MINIFOR Bioreactor and Fermenter along with the accessories for batch, fed-batch and continuous cultures, antifoam control, gas mixing module, medium cooling, outgas condensing, PC control software

31. REDOX potential measurement system

LAMBDA REDOX allows the measurement of the Red-Ox potential and the digital transfer of the data to the PC through its RS-485 interface. The measured data can be visualized and recorded for example by the fermentation software SIAM. The measurement of Red-Ox potential can be made with the laboratory fermenter-bioreactor LAMBDA MINIFOR, using a…

32. Medium cooling without cooling water

LAMBDA Peltier electronic cooling loop for MINIFOR fermenter-bioreactor Cooling with this device is based on the electronic cooling effect produced by the flow of electric current through a Peltier cell. The Peltier cell  allows cooling of the medium without the necessity of other means such as a refrigerating compressor or cooling water baths…

33. Autonomous precise gas flow control modules

LAMBDA MASSFLOW is a new mass flow controller system specially developed for the precise flow measurement and control of gases. It uses a high quality laminar mass flow sensor that has a very low pressure drop. The gas flow (e.g. air, oxygen, nitrogen, carbon dioxide, ...) is continuously measured and controlled. The flow rate is regulated by a…

34. Two PC fermentation software packages at the cost of one

Apart from the direct control of the parameter on the display, a process control system (PCS) for fully automatic control of the batch and data storage is available: FNet , an easy to use fermentation software for common cultures and up to 6 MINIFOR bioreactors is supplied in one package together with SIAM , a top notch industrial instrument…

35. Flow INTEGRATOR reveals valuable culture information

Integrator replaces the Optical Density (OD) measurement. It allows visualizing the amounts of acid or basis added as a function of time. The metabolism of all living organisms is somehow connected with the production or consumption of acids or bases. Thus, the metabolic activity can be calculated with much better precision than from difficult OD…

36. Extremely compact bioreactor system

LAMBDA invested a lot of energy and creativity to reduce the dimension of a laboratory fermenter and bioreactor system which could be carried away by a child. Because, the laboratory bench-space is the most expensive surfaces known. It really makes a sense in laboratory whether to have a single instrument or four instruments at the same bench…

37. Unique easy sterility construction

Elimination of critical points makes the keeping of bioreactor sterility easy. A strong silicone membrane isolates completely the vessel from the outer environment. The sterility is thus equivalent to magnetic coupling, but is considerably less complex and much less expensive. All o-rings have been replaced by large silicone stoppers with…

38. World smallest antifoam control system

To spare space around bioreactor vessels LAMBDA has developed the smallest anti-foam control system consisting of miniature foam detector ANTIFO and a subminiature syringe pump DOZITO. More about miniature antifoam controller and syringe pump. The LAMBDA MINIFOR laboratory bioreactor-fermenter can be equipped with a novel foam detector and control…

39. New softest agitation – the “Fish-Tail”

Agitation of cell cultures is problematic because the mechanically sensitive eukaryotic cells could be destroyed by the cutting edges of the stirrer. A special "fish-tail" stirring disc was developed for gentle up and down mixing both in horizontal and vertical direction. It is efficient and eliminates cutting edges and micro-eddies formed by all…

40. Exceptional volume range in one instrument

As there has been a lot of progress in analytics and sample preparation methods it is now possible to use, with advantages, much smaller volumes of media in smaller vessels than it was before. The MINIFOR fermenter-bioreactor has been conceived so that reliable results can be now obtained in much lower volume than before. No need to use 14, 10, 7…

41. Bioreactor - Overview and Benefits

Many different types of laboratory fermentors and bioreactors are used worldwide, but the selection of a good quality bioreactor is not easy. Some advantageous parameters found in one product are cancelled out by other drawbacks in the same system. We have put all the innovations together and released the new LAMBDA MINIFOR Bioreactor, which…

42. Self-cleaning micro-sparger

Common air spargers are frequently clogged especially in mineralized media. Due to the air flow the medium progressively dries out on the edge of the sparger orifices (openings) and eventually blocks them completely. This stops the air inflow and the run has to be aborted. LAMBDA introduces a self-cleaning micro-sparger, which due to its…

43. Specifications

Vessel types Vessel types: 0.3 0.4 1 3 7 . Volume [L]:  *) 0.035–0.4 0.15–0.45 0.3–1.7 0.5–3 1–6 Height [cm]:   **) 34 22 34 37 50 Diameter [cm]:   **) 22 23 25 34 30   *) Volume - is apx. minimal and maximal working volume. May vary according to conditions of each application. **)  Height + Diameter - apx. dimensions of the vessel…

44. Laboratory fermenter and bioreactor MINIFOR: The solitary team player in parallel processes

Why is MINIFOR perfectly suited for your parallel processes? Each unit stays independent “The MINIFOR fermenter-bioreactor is not only a solitary worker. You can also let it work in a team, in parallel cultures, without loss of independence in parameter regulation.” Each LAMBDA MINIFOR unit is equipped with a control panel and display and…

45. Innovation in application

A major effort has been invested in making applications of this bioreactor more efficient. This goal has been achieved in several steps Firstly, a replacement of the traditional rotation movement by an oscillating up and down movement of stirring discs driven by an electromagnet yields several important advantages. A soft, whole volume movement of…

46. Move it like a fish by efficient biomimetic stirring

Have you ever seen a fish with a marine propeller? Check out why fish-tail agitation is beneficial for your cells in lab-scale fermenters and bioreactors. Learn more!

47. LAMBDA INTEGRATOR replaces the need for optical density (OD) measurements

Frequently scientists want to know how their culture grows and what its metabolic activity during biotransformation is. For that reason, they are looking for instruments which can measure the optical density (OD) of the culture. Optical density is a logarithmic function and increasing the number of light absorption unit by one means that the…

48. New low dead volume cell retention disc

Coming soon: LAMBDA is testing a new modular cell retention system, where the total filter surface can be selected by the user. This cell retention system will have efficient automatic back washing and an extremely small dead volume. In comparison to so-called spin filters this innovation will considerably increase the efficient volume of the…

49. Maximal accessibility and visibility

A cascade casing guarantees overall easy visibility, accessibility and handling. The display showing all parameters and control buttons is located in the front. Very good visibility into the vessel which is fixed on the first platform above the infrared radiator. Easily accessible probes, ports, tubing and stirring connections. Storage of bottles…

50. Optimized bioreactor vessel design

The very expensive, clumsy and complex to set up traditional metal head plates were completely eliminated (see Elimination of expensive head plates ) and replaced by new threaded glass vessels, which make ports manipulation as easy as screwing a cap on a bottle! The LAMBDA fermentation vessel has one central neck with large threads for fast and…

51. Novel non rotational mixing

We have rejected the commonly used stirring of medium by rotation (which is almost a dogma in the field). We were amazed to see how many advantages (at least in the laboratory scale) are obtained by a simple reciprocating up and down movement of stirring discs. It is possible to get an easy and complete separation of the inner and outer…

52. Precise electronic gas flow control

A precise electronic mass flow controller automatically adjusts the pH and pO2 by proportional and continuous gas flow control The gas flow measurement and proportional needle valve are microprocessor-controlled Exact gas volume information More about precise mass flow measurement and control. Gas flow control is an important factor in the…

53. Automatic recognition of the culture volume

A very compact control system, which will allow good measurement and control of all important parameters by the same unit, is preferable for the user. Living organisms are extremely complex and it is desirable to measure and control as many parameters as possible. This will help to identify problems when they possibly arise. Therefore, we decided…

54. Fully independent control

The LAMBDA MINIFOR bioreactor can be fully controlled and operated from the front panel. Together with the probes, controllers and pumps it forms an autonomous unit. All parameters can be immediately seen without any scrolling and can be adjusted from the front panel situated on a well visible place just in front of the culture vessel. Each…

55. Elimination of expensive head plates

Typical fermentation vessels require a rather complex fixing of head plates with many and very closely spaced ports and screws. Heavy head plates are expensive and the accessibility of all ports on their top is bad, especially in the case of low volume vessels. A new head plate is necessary for each vessel of different volume which leads to high…

56. Easy weight control for continuous cultures

The amount of medium in the MINIFOR fermenter-bioreactor can be kept constant by using a special weighing module placed under the front edge of the instrument. The harvesting pump will automatically keep the weight of the culture constant. Continuous cultures (chemostat) allow a considerable increase in productivity. In an equilibrated dilution…

57. Fermentor

The Minifor was developed as a result of the need to construct a small laboratory fermenter for volumes from 0.035 to 6 l. Easy to use and with the capacity to measure and control all the important parameters of the biological culture. Minimum space on the bench but with a good access to all parts. Several fermenters are suitable for the…

58. Short selection of LAMBDA customers:

A short selection of LAMBDA Laboratory Instrument's customer list all around the world

59. MINI-4-GAS - Automatic gas mixing

•4-gas-mix for stem cell & mammalian cell culturing •3-gas-mix for anaerobe fermentation •O2-enrichment for microbial systems & biofuel development MINI-4-GAS station: The automatic gas-mixing. What is it about? The MINIFOR bioreactor and fermentor system  is used for growing and testing bacteria, yeast, fungi, mammalian cells and…

60. Peristaltic Pump

Result of twenty years of laboratory experience, which leads to the systematic elimination of the imperfections found in other pumps on the market. Precise, reliable and most compact pump in its class. Well-proved mechanics of this pump includes flow rate programming and allows user up to 99 steps of time, which allows the creation of any flow…

61. MINIFOR and its use at universities and high schools

Why is the LAMBDA MINIFOR laboratory fermenter and bench-top bioreactor so attractive to universities and high schools? It’s not only because of its functionality and accuracy… The modular concept “In addition to the standard 1L vessel we can also supply 0.3L (with a minimal working volume of 35ml), 0.4L, 3L and 7L reactor vessels. The…

62. Tutorial video

Please let us introduce you 20 Innovations that make our Bioreactor the best solution for your lab! You can choose automatic or manual guide and see what makes a difference. Click here to start. Bioreactors LAMBDA MINIFOR Laboratory Bioreactors — aeration and mixing ↑ Up Fermentor / Fermenter / Fermentador / Fermenteur Bench-top laboratory…

63. How to compare the cost and real value of a laboratory fermentor-bioreactor?

This guide should help colleagues to judge better what they get for their money when buying a laboratory fermentor. Some producers try to lower the initial selling price by supplying equipment and components with minimal value. Unaware clients decide to buy lower priced instruments without consideration of the much lower value obtained, future…

64. Highest pump quality for continuous cultures

The high quality LAMBDA peristaltic pumps PRECIFLOW, MULTIFLOW, HIFLOW and MAXIFLOW have been specially developed for long term continuous processes like in fermentations and cell cultures . LAMBDA's unique tubing compressing mechanics reduces pulsation and is very gentle to the tubing. No clamps, fixings or stoppers are required to hold the…

65. All infographics concerning MINIFOR fermentors and bioreactors

Easy Sterility Concept - Laboratory Fermentor-Bioreactor Extremely compact fermentor-bioreactor system LAMBDA MINIFOR Optimized vessel design of  laboratory fermentor-bioreactor Antifoam Control System for the MINIFOR laboratory fermentor-bioreactor Sun-like Infra-red soft heating Process control software for monitoring fermentation and cell…

66. Integrator

Connected to the LAMBDA Peristaltic Pump and other LAMBDA instruments, the integrator will allow you to record how much liquid has been pumped as a function of time. It informs how much of the solution (acid or base for example) has been added to maintain a constant pH. This additional data will inform you about the kinetics of the process, its…

67. Revolutionary radiation heating

The vessel is heated from underneath by infrared radiation generated by a spiral heater of high heating power but very low heat capacity. Heat rays are concentrated by the gilded parabolic reflector with 98 % efficiency onto the bottom of the vessel, where about 50% is absorbed by the glass and about 50% is absorbed directly by medium. The result…

68. “Mysterious Bioreactor” at Tate Modern, London

The interactive and immersive installation on the hall with acoustics, music, lighting, flying objects and film is controlled by a lab at the back of a space, with MINIFOR bioreactor set-up and a computer system. The microorganisms growing within the MINIFOR bioreactor create patterns that will help to define or trigger the sequence of events in…

69. Bioreactor Manuals

English LAMBDA MINIFOR bench-top laboratory fermenter-bioreactor (pdf; 249 kB) Bench-top Laboratory Fermentor-Bioreactor LAMBDA MINIFOR - Operation manual (pdf; 16311 kB) LAMBDA MINIFOR Innovative Laboratory-scale Bioreactors — Overview and Benefits (pdf; 784 kB) LAMBDA MINIFOR laboratory fermenter and bioreactor - the solitary teamplayer in…

70. Privacy Policy

LAMBDA CZ s.r.o. Privacy Policy This Privacy Policy describes how your personal information is collected, used, and shared when you visit or make a purchase from www.fermenter.net (the “Site”). PERSONAL INFORMATION WE COLLECT When you visit the Site, we automatically collect certain information about your device, including information about…

71. Quotation

72. Contact Information

Mailing address: LAMBDA Laboratory Instruments GmbH Sihlbruggstrasse 105 CH-6340 Baar Switzerland - Europe Tel : +41 - 444 502 071 Fax : +41 - 444 502 072 Email:  sales@lambda-instruments.com LAMBDA CZ s.r.o. Lozíbky 1 CZ-61400 Brno CZECH REPUBLIC – EUROPE Hotline : +420 603 274 677 Email: support@lambda-instruments.com